Related Experiment Video
Updated: Jul 20, 2026
09:16
Orthotopic Small Bowel Transplantation in Rats
Published on: November 6, 2012
Gastrointestinal complications following transplantation
1Brown Medical School, Division of Organ Transplantation, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA. amitabh_gautam@brown.edu
The Surgical Clinics of North America
|September 12, 2006
Summary
Gastrointestinal complications frequently occur after solid organ transplantation. Identifying the exact cause of these issues can be challenging due to multiple potential contributing factors.
Area of Science:
- Gastroenterology
- Transplant Medicine
- Immunology
Background:
- Gastrointestinal (GI) complications are a significant concern in patients undergoing solid organ transplantation.
- These complications can arise from pre-existing conditions, infections, or medication side effects.
Purpose of the Study:
- To review the common gastrointestinal complications following various solid organ transplantations.
- To highlight the diverse etiologies contributing to GI issues in transplant recipients.
Main Methods:
- Literature review of gastrointestinal complications in kidney, liver, pancreas, heart, and lung transplant recipients.
- Analysis of contributing factors including pre-transplant conditions, infections, and immunosuppressive medications.
Main Results:
- Gastrointestinal issues are prevalent across multiple solid organ transplant types.
- Etiologies are multifactorial, involving pre-transplant GI conditions, infections (viral, fungal, bacterial), and drug-induced side effects.
Conclusions:
- A comprehensive diagnostic approach is essential to determine the cause of GI complaints in transplant patients.
- Management requires consideration of the complex interplay between the transplant, patient's health status, and medications.
Related Concept Videos
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
01:16Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
01:24Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:15Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...