Related Experiment Video
Updated: Jul 20, 2026
08:27
Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
Eikenella corrodens in head and neck infections
Tsuyoshi Udaka1, Nobuaki Hiraki, Teruo Shiomori
1Department of Otorhinolaryngology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
The Journal of Infection
|September 12, 2006
Summary
Eikenella corrodens head and neck infections are common in tonsils, even in healthy individuals. Effective treatments include third-generation cephems, carbapenems, or new quinolones.
Area of Science:
- Otorhinolaryngology
- Infectious Diseases
- Microbiology
Background:
- Eikenella corrodens, a Gram-negative bacillus, is increasingly recognized as a pathogen in head and neck infections.
- Infections occur in both immunocompromised and immunocompetent individuals.
Purpose of the Study:
- To investigate the characteristics of Eikenella corrodens head and neck infections.
- To determine antimicrobial susceptibility patterns for effective treatment.
Main Methods:
- Retrospective analysis of 22 patients with E. corrodens head and neck infections.
- Microbial cultures (aerobic and anaerobic) and antimicrobial susceptibility testing (broth microdilution).
Main Results:
- Infections most commonly affected the tonsils (10/12 pharyngeal cases).
- Polymicrobial infections were frequent, often involving Staphylococcus and Streptococcus species.
- E. corrodens showed susceptibility to third-generation cephems, carbapenems, and new quinolones, but resistance to oxacillin, cefazolin, macrolides, and clindamycin.
Conclusions:
- E. corrodens head and neck infections, particularly tonsillar infections, occur in immunocompetent hosts.
- Co-infections with Streptococcus milleri group bacteria and use of ineffective antibiotics can worsen outcomes.
- Third-generation cephems, carbapenems, or new quinolones are recommended as first-line treatments.
Related Concept Videos
01:29Endocarditis IV: Nursing Management
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:25Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
01:26Arteries of the Head and Neck
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
01:29Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...