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Keeping the memory of smallpox virus

B Puissant1, B Combadière

  • 1INSERM U543, Laboratoire d'Immunologie Cellulaire et Université Pierre et Marie Curie (UPMC) Paris 6, Room 605, Institut National de la Santé et de la Recherche Médicale, 91 boulevard de l'hôpital, 75634, Paris Cedex 13, France.

Cellular and Molecular Life Sciences : CMLS
|September 12, 2006
PubMed

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Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...