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Published on: August 1, 2025
[Transfusion-transmitted virus (TTV) and renal failure]
Faissal Tarrass1, Jean Louis Koenig, Fanny Leroy
1Service d'hémodialyse, hôpitaux Drôme-Nord (Site de Romans), BP 1002, route du Tain, 26100 Romans-sur-Isère, France. faissal76@hotmail.com
Transfusion-Transmitted Virus (TTV), a DNA virus discovered in 1997, is linked to post-transfusion hepatitis. This review examines TTV
Area of Science:
- Virology
- Hepatology
- Nephrology
Context:
- Transfusion-Transmitted Virus (TTV) is a globally prevalent DNA virus.
- TTV infection is primarily observed in individuals with parenteral exposure risks, including those with chronic liver disease.
- Limited research exists on TTV epidemiology and its significance in renal disease patients.
Purpose:
- To review the characterization, discovery, taxonomy, and identification of TTV.
- To summarize the current understanding of TTV infection status in patients with renal diseases.
Summary:
- This paper provides a comprehensive review of Transfusion-Transmitted Virus (TTV).
- It covers the virus's characteristics, historical discovery, classification, and identification methods.
- The review consolidates available data on TTV prevalence and implications within the renal disease patient population.
Impact:
- Highlights knowledge gaps regarding TTV in renal disease patients.
- Provides a foundational resource for future research on TTV epidemiology and clinical relevance in nephrology.
- Aids in understanding the broader impact of TTV infection beyond liver disease.
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