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Sub-cutaneous phaeohyphomycosis caused by Cladophialophora devriesii in a United Kingdom resident
S J Howard1, S L Walker, S M Andrew
1Regional Mycology Laboratory, Hope Hospital, Manchester, UK. showard@fs1.ho.man.ac.uk
Abstract:
An 83-year-old diabetic man receiving corticosteroids developed a forearm lesion. Histology confirmed the presence of a dematiaceous fungus, with associated granulomatous inflammation. Culture of a biopsy yielded fungal colonies with branching chains of single-celled, melanised, dry, sympodial conidia, which were identified as Cladophialophora devriesii on the basis of morphology and rDNA gene sequencing. To date, C. devriesii has been a relatively rare cause of human disease. To our knowledge, this is only the second case to be described, and the first report of infection in a UK resident.
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