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Progressive resistance exercise for people with multiple sclerosis.

N F Taylor1, K J Dodd, D Prasad

  • 1Musculoskeletal Research Centre, School of Physiotherapy, Faculty of Health Sciences, La Trobe University, Victoria, 3086, Australia. N.Taylor@latrobe.edu.au

Disability and Rehabilitation
|September 13, 2006
PubMed
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Progressive resistance exercise (PRE) improved muscle strength, endurance, and walking speed in individuals with multiple sclerosis (MS). This safe and effective program enhanced physical function and psychological well-being for those with mild to moderate MS disability.

Area of Science:

  • Neurology
  • Exercise Physiology
  • Rehabilitation Science

Background:

  • Multiple Sclerosis (MS) is a chronic neurological condition impacting physical and psychological function.
  • Limited research exists on the efficacy of progressive resistance exercise (PRE) for individuals with MS.

Purpose of the Study:

  • To evaluate the effects of a 10-week PRE program on muscle force, endurance, and functional capacity in people with MS.
  • To assess the impact of PRE on the psychological well-being of individuals with MS.

Main Methods:

  • A pre-post single-group design with a 4-week familiarization period was employed.
  • Nine participants with MS completed a twice-weekly PRE program, with outcome measures assessed at multiple time points.
  • Key assessments included muscle strength (1RM), muscle endurance, walking speed, 2-minute walk test, and timed stairs test.

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Main Results:

  • Significant improvements were observed in arm strength (14.4%) and leg endurance (170.9%).
  • Fast walking speed increased by 6.1%, with a trend towards improved performance on the 2-minute walk test (P = 0.06).
  • The perceived impact of MS on physical function significantly decreased (P = 0.02), with no adverse events reported.

Conclusions:

  • Progressive resistance exercise is a safe and beneficial intervention for adults with mild to moderate multiple sclerosis.
  • PRE programs can enhance muscle performance, functional mobility, and reduce the physical impact of MS.
  • These findings support PRE as a feasible and valuable fitness option for managing MS-related disability.