Related Experiment Video

Updated: Jul 20, 2026

The Intra-Aortic Balloon Pump
06:13

The Intra-Aortic Balloon Pump

Published on: February 5, 2021

Hemodynamic energy generated by a combined centrifugal pump with an intra-aortic balloon pump

Choon Hak Lim1, Ho Sung Son, Yung Hu Fang

  • 1Anesthesiology and Pain Medicine, Korea University, Seoul, Korea.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|September 13, 2006
PubMed

Insights

The intra-aortic balloon pump/centrifugal pump (IABP/CP) combination effectively generated pulsatile flow, significantly increasing pulse pressure, energy equivalent pressure (EEP), and surplus hemodynamic energy (SHE) in a cardiac-arrested pig model.

Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Hemodynamics

Background:

  • Mechanical circulatory support aims to restore hemodynamic function.
  • Assessing the pulsatility and energy transfer of combined devices is crucial for optimizing circulatory support.

Purpose of the Study:

  • To evaluate the pulsatility and hemodynamic energy generated by an intra-aortic balloon pump/centrifugal pump (IABP/CP) combination.
  • To compare the hemodynamic effects of CP alone versus IABP/CP in a cardiac-arrested animal model.

Main Methods:

  • Utilized a cardiac-arrested pig model with cannulation of the right atrium and ascending aorta for extracorporeal circulation.
  • Integrated an intra-aortic balloon pump (IABP) into the descending aorta alongside the centrifugal pump (CP).
  • Measured hemodynamic parameters including pulse pressure, energy equivalent pressure (EEP), and surplus hemodynamic energy (SHE) in the carotid artery.

Main Results:

  • The IABP/CP combination significantly increased pulse pressure from 9.1 +/- 1.3 mm Hg to 54.9 +/- 6.1 mm Hg (p = 0.012).
  • A significant increase in the percent change from mean arterial pressure to EEP (0.2 +/- 0.3% to 23.3 +/- 6.1%, p = 0.012) and SHE (133.2 +/- 234.5 erg/cm to 20,219.8 +/- 5842.7 erg/cm3, p = 0.012) was observed with IABP/CP.
  • No significant difference in mean carotid artery pressure was found between CP alone and IABP/CP.

Conclusions:

  • The IABP/CP combination effectively converts non-pulsatile flow to pulsatile flow.
  • This combination significantly enhances hemodynamic energy parameters (EEP and SHE), suggesting improved circulatory support.
  • The IABP/CP system shows promise for augmenting pulsatility in mechanical circulatory support, particularly in critical care settings.

More Related Videos

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart08:49

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

Related Concept Videos

Application of the Energy Equation01:04

Application of the Energy Equation

The application of the energy equation to centrifugal pumps is a fundamental principle in fluid dynamics and engineering. In this scenario, the energy equation is used to calculate the flow rate of a centrifugal pump responsible for transferring water between two reservoirs at different elevations. The pump applies an energy input of 7500 joules per second, and the vertical difference between the lower and upper reservoirs is 10 meters. Additionally, the head loss due to friction and other...
Energy Conservation and Bernoulli's Equation01:16

Energy Conservation and Bernoulli's Equation

Applying the conservation of energy principle or the work-energy theorem to an incompressible, inviscid fluid in laminar, steady, irrotational flow leads to Bernoulli's equation. It states that the sum of the fluid pressure, potential, and kinetic energy per unit volume is constant along a streamline.
All the terms in the equation have the dimension of energy per unit volume. The kinetic energy per unit volume is called the kinetic energy density, and the potential energy per unit volume is...
Conservation of Energy in Control Volume01:14

Conservation of Energy in Control Volume

Consider a turbine operating under steady-flow conditions. The control volume is drawn around the turbine, with fluid entering at one point and exiting at another. The turbine extracts energy from the fluid, which performs mechanical work (shaft work).
For steady flow systems, the time derivative of the stored energy becomes zero since there is no energy accumulation within the control volume. This simplifies the energy equation to:
Bernoulli's Equation00:59

Bernoulli's Equation

In the middle of the nineteenth century, it was observed that two trains passing each other at a high relative speed get pulled towards each other. The same occurs when two cars pass each other at a high relative speed. The reason is that the fluid pressure drops in the region where the fluid speeds up. As the air between the trains or the cars increases in speed, its pressure reduces. The pressure on the outer parts of the vehicles is still the atmospheric pressure, while the resultant...