[Quality of life in patients with coronary artery disease: comparison between the genders]
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Maria Elenita Corrêa de Sampaio Favarato1, Desidério Favarato, Whady Armindo Hueb
1Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, USP, São Paulo, SP. psielenita@incor.usp.br
Insights
Surgical treatment for coronary artery disease (CAD) showed the best quality of life outcomes. Men experienced better initial quality of life and sustained improvement, unlike women who declined after six months.
Area of Science:
- Cardiology
- Health Outcomes Research
Background:
- Coronary artery disease (CAD) significantly impacts patient quality of life.
- Therapeutic interventions for CAD vary, necessitating an analysis of their long-term effects on well-being.
Purpose of the Study:
- To evaluate and compare the quality of life (QoL) in patients with CAD undergoing different treatments.
- To investigate gender-based differences in QoL following CAD interventions.
Main Methods:
- A cohort of 542 CAD patients (376 men, 166 women) received surgical, medical, or angioplasty treatment.
- Quality of life was measured using the SF-36 survey at baseline, 6, and 12 months post-treatment.
- ANOVA statistical tests were employed to analyze the data.
Main Results:
- Surgical treatment yielded the most favorable physical and mental component scores over 12 months.
- All treatment groups showed statistically significant improvements in QoL over time (p<0.001).
- Men consistently reported higher QoL scores than women, with significant gender differences observed (p<0.0001).
Conclusions:
- Surgical intervention appears to offer the most beneficial QoL trajectory for CAD patients.
- Men demonstrated a sustained improvement in QoL, whereas women experienced a decline after 6 months post-treatment.
- Gender disparities in QoL outcomes following CAD treatment warrant further investigation and tailored management strategies.
Objective:
To analyze the quality of life of people with coronary artery disease (CAD) who underwent distinct therapeutic interventions and compare the possible differences between genders.
Methods:
This study comprised 542 subjects, 376 men (58.5 +/- 8.7 years) and 166 women (61.8 +/- 9.2 years), with CAD who underwent surgical, medical treatment or angioplasty. Quality of life was assessed with The Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) administered at the beginning of treatment and after 6 and 12 months. The applied statistical method was the ANOVA test.
Results:
Those who underwent surgical treatment had scores of 46, 63, 68, for physical components; 52, 65, 62 for medical treatment, and 57, 66, 70 for angioplasty, respectively, in the initial, six, and twelve months phases. For mental components, results were 58, 71, 74 for the surgical intervention; 61, 69, 69 for the medical treatment, 64, 74, 74 for angioplasty. The differences over time and between treatments reached a statistical significance (p<0.001). In comparing genders, physical component scores in men were 56*, 69, 77*, and 41*, 64, 62* in women, respectively; mental component scores in men were 61*, 73, 80* and 51*, 68, 62* in women (*p<0.0001).
Conclusions:
Subjects who underwent surgical treatment had the most favorable evolution. Men when compared to women had a better quality of life in the beginning of treatment with a progressive improvement after six and twelve months, while women, after an improvement at six months, presented a decrease at twelve.
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Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...