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Related Experiment Video

Updated: Jul 20, 2026

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

Management of methamphetamine abuse and dependence.

Walter Ling¹, Richard Rawson, Steve Shoptaw

¹Integrated Substance Abuse Programs, David Geffen School of Medicine at UCLA, University of California-Los Angeles, 11075 Santa Monica Boulevard, Suite 200, Los Angeles, CA 90025, USA. lwalter@ix.netcom.com

Current Psychiatry Reports

|September 14, 2006

Summary

New research offers insights into methamphetamine dependence and its medical effects. Promising medications like bupropion and modafinil show potential for treating addiction and improving therapy outcomes.

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Area of Science:

Neuroscience
Pharmacology
Addiction Medicine

Background:

Methamphetamine dependence is a significant global health issue.
Impacts diverse subgroups including youth, women, and rural populations.
Complex consequences necessitate tailored, contextualized treatment approaches.

Purpose of the Study:

To explore new research findings on methamphetamine dependence.
To identify potential pharmacologic interventions.
To inform evidence-based treatments and future clinical practice.

Main Methods:

Review of neurobiological data on cellular activity.
Integration of findings from neuroimaging studies.
Analysis of early clinical trials for candidate medications.

Main Results:

Neurobiological and neuroimaging data suggest potential pharmacologic targets.
Bupropion and modafinil show promise in treating methamphetamine dependence.
Candidate medications may improve memory function for behavioral therapy.

Conclusions:

Emerging research provides a fresh perspective on methamphetamine addiction.
Pharmacologic interventions show potential for treating dependence.
Collaboration between clinicians and researchers is crucial for addressing this public health problem.