Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jul 20, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

[PET and malignant cerebral tumors].

Jean-Noël Talbot¹, Khaldoun Kerrou, Nicolas Gault

¹Service de Médecine Nucléaire, AP-HP Hôpital Tenon, Université Pierre et Marie Curie, Paris. jean-noel.talbot@tnn.ap-hop-paris.fr

Presse Medicale (Paris, France : 1983)

|September 14, 2006

Summary

Fluorodeoxyglucose (FDG) PET imaging aids in detecting brain cancers like gliomas and lymphomas. New PET tracers, including FET and FDOPA, show promise for improved brain tumor visualization and treatment guidance.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Focal congenital hyperinsulinism: spontaneous glycemic improvement before surgery.

The Journal of clinical endocrinology and metabolism·2026

Same author

Functional Estrogen Receptor Assessment: Insights From Discordant 18 F-FES PET/CT and ER Immunohistochemistry.

Clinical nuclear medicine·2026

Same author

Efficacy of immune checkpoint inhibitors in paediatric, adolescent and young adults with primary refractory or relapsed classical Hodgkin lymphoma: A national multicentre real-world study.

British journal of haematology·2026

Same author

Robotic versus Open Pancreatectomy for Focal Congenital Hyperinsulinism in Infants: A Single-Center Study.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie·2026

Same author

Renal hyperparathyroidism: preoperative detection of abnormal parathyroid glands by 18F-fluorocholine PET/CT and ultrasonography. Comparison of diagnostic performance and optimization of imaging sequence based on 159 paired examinations.

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...·2025

Same author

68 Ga-NODAGA-EXENDIN-4 PET/CT in the Detection or the Exclusion of Occult Sporadic Insulinomas.

Clinical nuclear medicine·2025

Area of Science:

Nuclear Medicine
Oncology
Radiochemistry

Background:

Physiologic glucose uptake in the brain complicates the detection of malignant lesions using FDG PET.
Despite limitations, FDG PET is valuable for identifying high-grade gliomas, lymphomas, and unexpected brain metastases.

Purpose of the Study:

To evaluate the clinical utility of FDG PET in brain tumor detection and management.
To highlight the effectiveness of novel PET radiopharmaceuticals, specifically FET and FDOPA, in delineating brain tumors.

Main Methods:

Review of clinical cases utilizing FDG PET for brain tumor diagnosis and follow-up.
Presentation of four original cases showcasing the performance of Fluorine-18-FET (FET) and Fluorine-18-FDOPA (FDOPA) PET.

More Related Videos

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device

Published on: May 2, 2025

Related Experiment Videos

Last Updated: Jul 20, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device

Published on: May 2, 2025

Main Results:

FDG PET assists in stereotactic radiosurgery precision and differentiating tumor recurrence from post-treatment changes.
Methionine-(11C) PET accurately delineates low-grade gliomas.
FET and FDOPA PET demonstrate significant potential as effective radiopharmaceuticals for brain tumor imaging.

Conclusions:

FDG PET remains a useful adjunct in neuro-oncology, particularly for high-grade lesions.
Emerging PET tracers like FET and FDOPA offer improved diagnostic capabilities for various brain tumors, including low-grade gliomas.