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Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications
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Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications

Published on: June 23, 2016

Unmodified gold nanoparticles as a colorimetric probe for potassium DNA aptamers

Lihua Wang1, Xingfen Liu, Xiaofang Hu

  • 1Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.

Chemical Communications (Cambridge, England)
|September 14, 2006
PubMed

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Labeling DNA Probes03:31

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...