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Published on: November 8, 2011
B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express the CD5 T cell marker
J J Letesson1, A Mager, M Mammerickx
1Microbiology and Immunology Unit, Universite Notre Dame de la Paix Namur, Belgium.
Though peripheral blood B cells from healthy sheep were known to be devoid of the CD5 T cell marker, it appears from our study that most B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express both the CD5 marker and surface IgM. The possible meaning of this T cell marker expression on B cells from BLV-infected sheep is briefly discussed.
Though peripheral blood B cells from healthy sheep were known to be devoid of the CD5 T cell marker, it appears from our study that most B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express both the CD5 marker and surface IgM. The possible meaning of this T cell marker expression on B cells from BLV-infected sheep is briefly discussed.

