Related Experiment Video

Updated: Jul 20, 2026

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
05:25

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

[Comparative study of overactive bladder prevalence in patients younger than 50 years with and without

Salvador Rafael Solano Sánchez1, María Pilar Velázquez Sánchez, Silvia Rodríguez Colorado

  • 1Instituto Nacional de Perinatologia. srss27@yahoo.com

Ginecologia Y Obstetricia De Mexico
|September 15, 2006
PubMed

Insights

This study found a link between hyperprolactinemia and idiopathic overactive bladder. Elevated prolactin levels are associated with overactive bladder symptoms in patients.

Area of Science:

  • Urology
  • Endocrinology

Background:

  • Idiopathic overactive bladder (OAB) is a common condition with significant impact on quality of life.
  • Hyperprolactinemia, elevated prolactin levels, has been investigated for various non-reproductive effects.

Purpose of the Study:

  • To investigate the potential association between hyperprolactinemia and idiopathic overactive bladder.
  • To determine if elevated prolactin levels correlate with OAB symptoms.

Main Methods:

  • A transversal, analytic study was conducted.
  • 160 patients with measured plasma prolactin levels were included.
  • An eight-question diagnostic questionnaire was used to assess overactive bladder, and chi-square statistical analysis was applied.

Main Results:

  • A relative prevalence of 2.82 (95% CI: 1.45-3.17) was observed.
  • A statistically significant association was determined between hyperprolactinemia and overactive bladder.

Conclusions:

  • Hyperprolactinemia is associated with idiopathic overactive bladder.
  • This finding suggests a potential role for prolactin in the pathophysiology of OAB.
Abstract

Related Concept Videos

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...