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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

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Published on: June 2, 2014

Migraine prophylaxis: who, why, and how.

Jadwiga Loj¹, Glen D Solomon

¹Department of Medicine, Advocate Lutheran General Hospital, Park Ridge, IL 60068, USA.

Cleveland Clinic Journal of Medicine

|September 15, 2006

Summary

For frequent, severe migraine headaches, prophylactic treatment can help. Medications like beta-blockers, antidepressants, and anticonvulsants are effective options for migraine prevention.

Area of Science:

Neurology
Pharmacology

Background:

Migraine headaches are a common neurological condition causing severe, debilitating pain.
Frequent migraines significantly impact patient quality of life.
Prophylactic treatment is a key strategy for managing recurrent migraine attacks.

Purpose of the Study:

To review current migraine treatment strategies.
To emphasize the role of prophylactic treatments in managing frequent and severe migraines.
To discuss the efficacy and tolerability of various prophylactic drug classes.

Main Methods:

Literature review of studies on migraine prophylaxis.
Analysis of evidence for different drug classes used in migraine prevention.
Evaluation of treatment options based on efficacy, tolerability, and cost.

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Main Results:

Beta-blockers, tricyclic antidepressants, and anticonvulsants demonstrate the strongest evidence for migraine prophylactic efficacy.
Calcium channel blockers and nonsteroidal anti-inflammatory drugs are frequently used due to good tolerability and low cost.
Several medication classes offer viable options for reducing migraine frequency and severity.

Conclusions:

Prophylactic treatment is essential for patients with frequent, severe migraines.
A range of medications, including beta-blockers, antidepressants, and anticonvulsants, are effective for migraine prevention.
Treatment choice should consider efficacy, side effect profile, and patient cost.