Related Experiment Video
Updated: Jul 20, 2026

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
Published on: November 8, 2016
[Advances in the study of steroidogenic acute regulatory protein]
1Department of Toxicology, Nanjing Medical University, Nanjing, Jiangsu 210029, China. caoyewang@yahoo.com.cn
Abstract:
The steroidogenic acute regulatory (StAR) protein is an essential component in the regulation of steroid biosynthesis in adrenal and gonadal cells. The StAR protein has a high tissue specificity, located on the mitochondrial membranes of some relative cells. It regulates the transfer of cholesterin from extracellular into intracellular and plays a dominant role in steroidogenic synthesis. Recent studies have also shown that the transcription and expression of StAR are modulated not only through the cAMP-PKA dependent pathway, but also by multiple hormones and cytokines, which contributes to the regulation of cholesterin synthesis.
Related Concept Videos
Regulation of Nuclear Protein Sorting
Global Regulatory Systems
Transducer Mechanism: Nuclear Receptors
About 48 different soluble family members of nuclear receptors are identified that can be divided into two main classes:
Co-activators and Co-repressors
GPCRs Regulate Adenylyl Cylase Activity
Two...
Master Transcription Regulators
