Live/real time three-dimensional echocardiographic demonstration of left ventricular noncompaction and thrombi

Pridhvi Yelamanchili1, Navin C Nanda, Vinod Patel

  • 1Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA.

Insights

Live three-dimensional transthoracic echocardiography (3DTTE) improved diagnosis of left ventricular noncompaction by clearly showing coexisting clots and trabeculations. 3DTTE distinguished mobile clots from trabeculations, aiding definitive diagnosis in two patients.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Left ventricular noncompaction (LVNC) is a rare cardiomyopathy.
  • Accurate diagnosis of LVNC and associated complications like thrombus formation is crucial for patient management.
  • Distinguishing between trabeculations and intracardiac thrombi can be challenging with conventional imaging.

Observation:

  • Two adult patients with suspected left ventricular noncompaction were evaluated.
  • Conventional two-dimensional transthoracic echocardiography (2DTTE) was supplemented with live/real-time three-dimensional transthoracic echocardiography (3DTTE).
  • 3DTTE provided enhanced visualization of the left ventricular полости.

Findings:

  • 3DTTE facilitated a definitive diagnosis of coexisting thrombi and trabeculations in the left ventricle for both patients.
  • The mobility of thrombi and presence of central echolucencies, indicative of clot lysis, were clearly demonstrated by 3DTTE.
  • 3DTTE enabled confident differentiation between mobile thrombi and adjacent noncompacted trabeculations.

Implications:

  • Live 3DTTE is a valuable tool for improving diagnostic accuracy in complex cases of left ventricular noncompaction.
  • This advanced echocardiographic technique aids in differentiating intracardiac thrombi from trabeculations, potentially impacting treatment strategies.
  • Enhanced visualization of thrombus characteristics by 3DTTE may improve risk stratification and therapeutic decision-making in LVNC patients.