Related Experiment Video
Updated: Jul 20, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Live/real time three-dimensional echocardiographic demonstration of left ventricular noncompaction and thrombi
Pridhvi Yelamanchili1, Navin C Nanda, Vinod Patel
1Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA.
Insights
Live three-dimensional transthoracic echocardiography (3DTTE) improved diagnosis of left ventricular noncompaction by clearly showing coexisting clots and trabeculations. 3DTTE distinguished mobile clots from trabeculations, aiding definitive diagnosis in two patients.
Area of Science:
- Cardiology
- Medical Imaging
- Echocardiography
Background:
- Left ventricular noncompaction (LVNC) is a rare cardiomyopathy.
- Accurate diagnosis of LVNC and associated complications like thrombus formation is crucial for patient management.
- Distinguishing between trabeculations and intracardiac thrombi can be challenging with conventional imaging.
Observation:
- Two adult patients with suspected left ventricular noncompaction were evaluated.
- Conventional two-dimensional transthoracic echocardiography (2DTTE) was supplemented with live/real-time three-dimensional transthoracic echocardiography (3DTTE).
- 3DTTE provided enhanced visualization of the left ventricular полости.
Findings:
- 3DTTE facilitated a definitive diagnosis of coexisting thrombi and trabeculations in the left ventricle for both patients.
- The mobility of thrombi and presence of central echolucencies, indicative of clot lysis, were clearly demonstrated by 3DTTE.
- 3DTTE enabled confident differentiation between mobile thrombi and adjacent noncompacted trabeculations.
Implications:
- Live 3DTTE is a valuable tool for improving diagnostic accuracy in complex cases of left ventricular noncompaction.
- This advanced echocardiographic technique aids in differentiating intracardiac thrombi from trabeculations, potentially impacting treatment strategies.
- Enhanced visualization of thrombus characteristics by 3DTTE may improve risk stratification and therapeutic decision-making in LVNC patients.
Abstract:
We describe two adult patients with left ventricular noncompaction in whom live/real time three-dimensional transthoracic echocardiography (3DTTE) supplemented two-dimensional transthoracic echocardiography in making a definitive diagnosis of clots coexisting with trabeculations in the left ventricle. Mobility of clots and the presence of central echolucencies consistent with clot lysis were best demonstrated by 3DTTE and served to confidently differentiate clots from adjacent trabeculations.
More Related Videos
03:40Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
Published on: January 17, 2025
06:48Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
Published on: October 28, 2020
Related Concept Videos
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...