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Renal masses: characterization with Doppler US.

R Kier1, K J Taylor, A L Feyock

  • 1Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06510.

Radiology
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

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Duplex ultrasound can help differentiate benign from malignant renal masses by analyzing blood flow signals. High-frequency Doppler shifts (≥2.5 kHz) indicate neovascularity, aiding in the diagnosis of kidney tumors.

Area of Science:

  • Nephrology
  • Radiology
  • Medical Imaging

Background:

  • Distinguishing between benign and malignant renal masses is crucial for patient management.
  • Indeterminate renal masses present a diagnostic challenge.
  • Vascularity assessment can aid in differentiating renal lesions.

Purpose of the Study:

  • To prospectively investigate the vascularity of indeterminate renal masses using duplex ultrasound.
  • To determine if peak-systolic Doppler shift frequency can distinguish between benign and malignant renal lesions.

Main Methods:

  • Prospective study of 70 patients with indeterminate renal masses.
  • Duplex ultrasound was used to assess renal mass vascularity.
  • Peak-systolic Doppler shift frequency was measured to detect neovascularity (criterion: ≥2.5 kHz).

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Main Results:

  • 70% sensitivity: 26 of 37 malignant lesions showed abnormal Doppler signals.
  • 94% specificity: 31 of 33 benign lesions lacked abnormal signals.
  • False positives included inflammatory masses (infections).

Conclusions:

  • Abnormal, high-frequency Doppler signals from tumor vascularity can aid in the differential diagnosis of renal masses.
  • Duplex ultrasound is a valuable tool for assessing renal mass vascularity.
  • Doppler ultrasound findings can help differentiate malignant from benign renal lesions.