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Epilepsy and neuropsychologic deficit in a child with cerebellar astrocytoma
Sandra Strazzer1, Claudio Zucca, Isabella Fiocchi
1IRCCS E. Medea, La Nostra Famiglia, via don Luigi Monza 20, 23842 Bosisio Parini, Lecco, Italy. sandrastrazzer@yahoo.it
Insights
A pediatric cerebellar pilocytic astrocytoma presented atypically with seizures and developmental delays, not typical tumor symptoms. This case highlights the cerebellum's role in nonmotor functions, especially post-surgery.
Area of Science:
- Pediatric Neurology
- Neuro-oncology
- Developmental Neuroscience
Background:
- Cerebellar pilocytic astrocytomas typically present with symptoms of increased intracranial pressure and ataxia.
- Epileptic seizures are an uncommon presenting symptom for focal cerebellar masses.
Observation:
- A 32-month-old female exhibited cerebellar pilocytic astrocytoma with initial symptoms of epileptic seizures, psychomotor delay, and severe language delay.
- This presentation contrasts with the usual onset of cerebellar tumors.
Findings:
- Literature review identified few cases of cerebellar tumors presenting primarily with epileptic seizures.
- The cerebellar pilocytic astrocytoma in this case was a focal, nondegenerative mass.
Implications:
- The cerebellum plays a significant role in nonmotor functions in children, including language and cognition.
- Understanding atypical presentations is crucial for early diagnosis and management of pediatric brain tumors.
- Cerebellar function in nonmotor domains may be impacted by tumor resection, necessitating further investigation.
Abstract:
We report the case of a 32-month-old female patient presenting with cerebellar pilocytic astrocytoma with epileptic seizures, psychomotor delay, and severe language delay. Usually, the typical onset of cerebellar tumor is characterized by raised intracranial pressure and cerebellar incoordination. A review of the few cases reported in the literature evidencing epileptic seizures symptomatic of a focal, nondegenerative mass limited to the cerebellum is included. Moreover, a discussion about the cerebellar contribution to nonmotor functions in children is presented, in particular following tumor resection.
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