Higher pertussis hospitalization rates in indigenous Australian infants, and delayed vaccination

Veronica Kolos1, Robert Menzies, Peter McIntyre

  • 1University of Sydney, Australia.

Vaccine
|September 15, 2006
PubMed

Insights

Higher pertussis hospitalization rates in Indigenous Australian infants are linked to delayed vaccination and living in remote areas. These factors contribute to increased risks for young Indigenous children.

Area of Science:

  • Public Health
  • Epidemiology
  • Indigenous Health

Background:

  • Pertussis (whooping cough) poses a significant health risk to infants.
  • Higher hospitalization rates for pertussis have been observed in Indigenous Australian infants.

Purpose of the Study:

  • To investigate the underlying factors contributing to elevated pertussis hospitalization rates among Indigenous Australian infants.
  • To analyze the impact of geographical location and vaccination timing on pertussis outcomes.

Main Methods:

  • Ecological study design utilizing national datasets.
  • Analysis of the Australian Hospital Morbidity Database.
  • Examination of data from the Australian Childhood Immunisation Register (ACIR).

Main Results:

  • 52% of pertussis hospitalizations in Indigenous infants occurred between 0-2 months of age.
  • Pertussis hospitalization rates were significantly higher in Indigenous infants residing in remote areas.
  • Indigenous infants experienced higher hospitalization rates and more frequent vaccination delays compared to non-Indigenous infants.

Conclusions:

  • Residence in remote areas, serving as an indicator of living conditions, is associated with increased pertussis hospitalization risk in Indigenous infants.
  • Delayed infant vaccination is a significant contributing factor to higher pertussis hospitalization rates in this population.
  • Interventions addressing vaccination access and living conditions in remote areas are crucial for reducing pertussis burden in Indigenous infants.

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...