Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Proteomics and transfusion medicine: future perspectives.

Pierre-Alain Queloz1, Lynne Thadikkaran, David Crettaz

  • 1Service régional vaudois de transfusion sanguine, Lausanne, Switzerland.

Proteomics
|September 15, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exposure of red blood cell concentrates to temperatures below 0°C for a short period does not alter in vitro quality.

Blood transfusion = Trasfusione del sangue·2026
Same author

Sequential combinations of rapid immunoassays for prompt recognition of heparin-induced thrombocytopenia.

Blood·2025
Same author

Biotinylation of human platelets is compatible with pathogen inactivation treatment and cold storage for clinical studies.

Transfusion·2024
Same author

Increase of Phosphoprotein Expressions in Amotosalen/UVA-Treated Platelet Concentrates.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie·2024
Same author

Phosphoproteomics and morphology of stored human red blood cells treated by protein tyrosine phosphatases inhibitor.

Blood advances·2023
Same author

The Effect of the Donor's and Recipient's Sex on Red Blood Cells Evaluated Using Transfusion Simulations.

Cells·2023

Proteomics offers new insights into blood product storage, revealing changes in peptides and proteins. This review explores proteomic tools and their potential to advance transfusion medicine safety and efficacy.

Area of Science:

  • Blood transfusion research
  • Proteomics
  • Biochemistry

Background:

  • Key discoveries like ABO blood groups and plastic bags have advanced blood transfusion.
  • Major blood products include red cells, platelets, and plasma, with storage-related changes extensively studied.
  • Peptide and protein alterations during blood product storage remain under-investigated.

Purpose of the Study:

  • To review the application of proteomic tools in transfusion medicine.
  • To highlight the potential of proteomics in understanding blood product changes.
  • To identify overlooked aspects of peptide and protein modifications during storage.

Main Methods:

  • Literature review of studies utilizing proteomic techniques in transfusion medicine.
  • Analysis of existing research on blood product storage parameters.

Related Experiment Videos

  • Exploration of proteomic methodologies applicable to blood products.

    • Main Results:

    • Proteomics has been applied to a limited extent in transfusion medicine.
    • Significant changes in peptide and protein profiles occur during blood product storage.
    • Proteomic analysis can reveal critical, previously ignored, molecular alterations.

    Conclusions:

    • Proteomics provides powerful tools to investigate changes in blood products during storage.
    • Further application of proteomics can enhance the safety and efficacy of transfusion medicine.
    • Understanding peptide and protein dynamics is crucial for optimizing blood product utilization.