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How practical are adaptive designs likely to be for confirmatory trials?

A Lawrence Gould1

  • 1Merck Research Laboratories, West Point, PA 19486, USA. larry_gould@merck.com

Biometrical Journal. Biometrische Zeitschrift
|September 16, 2006
PubMed
Summary

This discussion covers adaptive designs for clinical trials, focusing on seamless Phase II/III studies where hypotheses are selected during interim analyses. It explores general concepts and practical applications for efficient drug development.

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