Related Experiment Video
Updated: Jul 20, 2026
04:09
Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Capsule endoscopy in obscure gastrointestinal bleeding--an Indian experience
Rajesh Gupta1, Sandeep Lakhtakia, Manu Tandan
1Department of Medical Gastroenterology, Asian Institute of Gastroenterology, 6-3-661 Somajiguda, Hyderabad 500-082, India. aigindia@yahoo.co.in
Summary
Capsule endoscopy (CE) is valuable for diagnosing obscure gastrointestinal bleeding (OGIB). It shows a higher diagnostic yield in overt OGIB cases, aiding treatment planning.
Area of Science:
- Gastroenterology
- Medical Imaging
- Diagnostic Endoscopy
Background:
- Obscure gastrointestinal bleeding (OGIB) is a frequent reason for capsule endoscopy (CE).
- Existing reports show considerable variability in the diagnostic yield of CE for OGIB.
- This study aimed to assess CE's diagnostic yield and clinical impact in OGIB patients.
Purpose of the Study:
- To evaluate the diagnostic yield of capsule endoscopy (CE) in patients presenting with obscure gastrointestinal bleeding (OGIB).
- To determine the clinical impact of CE findings on subsequent patient management.
- To compare the diagnostic efficacy of CE in overt versus occult OGIB.
Main Methods:
- A retrospective review of medical records was conducted.
- Data from 154 patients with OGIB who underwent capsule endoscopy (CE) between June 2002 and October 2005 were analyzed.
- Patient demographics, CE findings, and subsequent management were recorded.
Main Results:
- The overall positive diagnostic yield for CE in OGIB was 52%.
- CE demonstrated a significantly higher diagnostic yield in overt OGIB (77%) compared to occult OGIB (27%).
- Common findings included NSAID-induced lesions (15%), angiodysplasias (14%), and aphthous ulcers (12%). CE influenced management in 79% of overt OGIB and 26% of occult OGIB cases.
Conclusions:
- Capsule endoscopy (CE) is an effective diagnostic tool for patients with obscure gastrointestinal bleeding (OGIB).
- CE is particularly beneficial for patients with overt OGIB, offering a higher diagnostic yield and guiding management decisions.
- The findings support the utility of CE in the diagnostic workup of OGIB.
Related Concept Videos
01:28Endoscopic Procedures III: Video Capsule Endoscopy
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers, unexplained...
01:28Esophageal Varices-II: Clinical Features and Management
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
01:26Endoscopic Procedures V: ERCP
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
01:29Endoscopic Procedures I: Esophagogastroduodenoscopy
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
01:25Endoscopic Procedures II: Colonoscopy
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections: