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Related Experiment Videos

[Pseudomigraine with pleocytosis].

Gabriela S Pariso1, Virginia L Parisi, Gabriel G Persi

  • 1Departamento de Neurología, Sanatorio de la Trinidad-Mitre, Buenos Aires.

Medicina
|September 19, 2006
PubMed
Summary
This summary is machine-generated.

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Transient headache and neurological deficits with cerebrospinal fluid lymphocytosis or pseudomigraine with temporary neurological symptoms and lymphocytic pleocytosis (HaNDL) is a rare syndrome. This case report details a patient experiencing migraine with pleocytosis and transient deficits, highlighting the importance of differential diagnosis.

Area of Science:

  • Neurology
  • Neuroscience
  • Clinical Neurology

Background:

  • Transient headache and neurological deficits with cerebrospinal fluid lymphocytosis or pseudomigraine with temporary neurological symptoms and lymphocytic pleocytosis (HaNDL) is a rare neurological syndrome.
  • Characterized by recurrent headaches, reversible neurological deficits, and lymphocytic pleocytosis in cerebrospinal fluid (CSF).
  • Etiology remains largely unknown despite proposed vascular, infectious, immunological, and calcium channelopathy mechanisms.

Observation:

  • A case of a 28-year-old female presenting with recurrent migraine accompanied by pleocytosis.
  • The patient also experienced a confusional syndrome and transient neurological deficits.
  • Clinical remission was observed within two months.

Findings:

Related Experiment Videos

  • The presented case aligns with the diagnostic criteria for HaNDL syndrome.
  • The patient's symptoms, including migraine, pleocytosis, and transient neurological deficits, resolved spontaneously.
  • This case underscores the variability in presentation and the importance of recognizing HaNDL.

    • Implications:

    • Accurate diagnosis of HaNDL syndrome is crucial for appropriate patient management.
    • Considering HaNDL in the differential diagnosis can prevent unnecessary investigations and treatments.
    • Further research into the etiopathogenesis of HaNDL is warranted to improve understanding and treatment strategies.