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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

Stenotrophomonas maltophilia resistant to trimethoprim-sulfamethoxazole: an increasing problem

Asma Marzouq Al-Jasser1

  • 1Department of Microbiology, Armed Forces Hospital, Box X-966, P.O. Box 7897, Riyadh - 11159, Saudi Arabia. asjass2002@yahoo.com

Annals of Clinical Microbiology and Antimicrobials
|September 19, 2006
PubMed

Insights

Stenotrophomonas maltophilia, a growing nosocomial threat, is becoming resistant to trimethoprim-sulfamethoxazole (TMP-SXT). This study reports the first documented TMP-SXT resistant S. maltophilia cases in Saudi Arabia.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Stenotrophomonas maltophilia is an emerging nosocomial pathogen.
  • Infections are challenging due to frequent antimicrobial resistance.
  • Trimethoprim-sulfamethoxazole (TMP-SXT) is the recommended treatment.

Observation:

  • This letter details the initial identification of S. maltophilia strains exhibiting resistance to TMP-SXT.
  • These resistant strains were isolated from two patients at Riyadh Armed Forces Hospital, a key tertiary care facility in Saudi Arabia.

Findings:

  • The study reports the first isolation of TMP-SXT resistant S. maltophilia in Saudi Arabia.
  • This highlights a significant challenge in treating S. maltophilia infections.

Implications:

  • The emergence of TMP-SXT resistance in S. maltophilia necessitates updated treatment guidelines.
  • This finding has critical implications for infection control and antimicrobial stewardship in the region.
  • Further surveillance and research are crucial to monitor and combat antimicrobial resistance in S. maltophilia.

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