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Unilateral reverse ocular bobbing caused by tuberous sclerosis.
Hakki Muammer Karakas1, Cengiz Yakinci, Ahmet Kemal Firat
1Department of Radiology, Turgut Ozal Medical Center, Inonu University Medical Faculty, Malatya, Turkey. hkarakas@inonu.edu.tr
Developmental Medicine and Child Neurology
|September 19, 2006
Summary
This study reports a rare case of ocular bobbing in a child with tuberous sclerosis. The condition presented with developmental delay and abnormal eye movements, highlighting a unique neurological manifestation.
Area of Science:
- Neurology
- Pediatrics
- Ophthalmology
Background:
- Tuberous sclerosis is a genetic disorder causing tumors in various organs.
- Ocular bobbing is an abnormal eye movement typically associated with severe brainstem lesions.
Observation:
- A 12-month-old female presented with developmental delay and left-sided reverse ocular bobbing.
- Initial diagnosis included a benign granular cell tumor, with CT and MRI revealing pontine lesions and white matter abnormalities characteristic of tuberous sclerosis.
Findings:
- The patient exhibited persistent reverse ocular bobbing despite relatively mild pontine pathology.
- This represents the first documented case of ocular bobbing associated with tuberous sclerosis.
Implications:
- This case expands the spectrum of ocular motor abnormalities in tuberous sclerosis.
- It suggests that ocular bobbing can occur with less severe brainstem involvement than previously thought.
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