[Delayed infection after Bio-alcamid implantation]

Area of Science:

• Dermatology
• Plastic Surgery
• Biomaterials Science

Background:

• Bio-alcamid (Polymekon) is a poly-alkyl-imide and water-based endoprosthesis used for aesthetic facial contouring.
• It is generally recognized for its high tolerance and minimal adverse effects in cosmetic procedures.
• Previous literature has limited documentation regarding infections associated with this specific biomaterial.

Observation:

• A case study involving a patient who received Bio-alcamid injections in the nasolabial furrows and lips is presented.
• Three months post-implantation, the patient developed a localized infection at one of the injection sites.
• This clinical presentation is unusual given the typical safety profile of the material.

Findings:

• The case highlights a delayed localized infection occurring three months after Bio-alcamid (Polymekon) injection.
• This represents a potentially novel complication, as delayed infections are not commonly reported for this poly-alkyl-imide filler.
• The findings suggest the possibility of late-onset inflammatory or infectious responses to the endoprosthesis.

Implications:

• This case underscores the importance of monitoring patients for delayed adverse events following Bio-alcamid injections.
• It may prompt further investigation into the long-term biocompatibility and potential infectious risks of poly-alkyl-imide fillers.
• Clinicians should consider delayed infection in the differential diagnosis for persistent inflammation or discomfort at injection sites, even months after aesthetic procedures.