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Updated: Jul 20, 2026
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Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
[The stereotactic body radiation therapy: initiation and clinical program].
1Service de Radiothérapie, Centre de Lutte Contre le Cancer Léon-Bérard, 28, Rue Laënnec, 69008 Lyon, France. gassa@lyon.fnclcc.fr
Summary
Stereotactic Body Radiation Therapy (SBRT) precisely targets tumors using advanced motion tracking and imaging. This innovative radiotherapy technique enables high-dose, hypofractionated treatment for solid tumors with reduced toxicity.
Area of Science:
- Radiation Oncology
- Medical Physics
- Oncology
Context:
- Stereotactic Body Radiation Therapy (SBRT) is an advanced radiotherapy technique.
- Clinical application of SBRT at the Léon-Bérard cancer center in Lyon, France.
- SBRT utilizes non-invasive stereotactic body frames for precise tumor localization.
Purpose:
- To describe the innovative Stereotactic Body Radiation Therapy (SBRT) technique.
- To explain the clinical application of SBRT for solid tumor treatment.
- To detail the technological components and methodologies employed in SBRT.
Summary:
- SBRT employs precise tumor localization via stereotactic body frames and respiratory motion management (Active Breathing Control or diaphragmatic compression) to minimize irradiated normal tissue.
- Dosimetry is confirmed with 3 CT scans, and 3D patient repositioning is achieved using volume CT and orthogonal kV/MV imaging.
- While Active Breathing Control offers smaller margins, it is incompatible with volume CT acquisitions that enhance repositioning accuracy.
Impact:
- High equivalent doses (>100 Gy) can be delivered in hypofractionated SBRT regimens.
- Reduced treatment margins and precise patient repositioning minimize toxicity.
- SBRT represents a significant advancement in radiotherapy, offering an effective tool for solid tumor management.
