Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic fatigue syndrome.

L D Devanur1, J R Kerr

  • 1Chronic Fatigue Syndrome (CFS) Group, Department of Cellular & Molecular Medicine, St. George's University of London, Cranmer Terrace, London SW17 0RE, United Kingdom.

Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
|September 19, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Boyle's Law ignores dynamic processes in governing barotrauma in fish.

Scientific reports·2023
Same author

The effects of simulated hydropower turbine rapid decompression on two Neotropical fish species.

The Science of the total environment·2023
Same author

Selective fish passage: Restoring habitat connectivity without facilitating the spread of a non-native species.

Journal of environmental management·2020
Same author

Altered expression and coregulation of dopamine signalling genes in schizophrenia and bipolar disorder.

Neuropathology and applied neurobiology·2010
Same author

Enhanced variance of irradiance from target glint.

Applied optics·2010
Same author

Optical propagation in laboratory-generated turbulence.

Applied optics·2010
Same journal

Predictive models for graft rejection and infections in renal transplant patients based on TTV viral load.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026
Same journal

Clinical evaluation of the Altostar HDV RT-PCR Kit 1.5.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026
Same journal

Discordant trends in enteroviral infections and meningitis in the post-COVID-19 era: Contributions of type distribution and type-specific risk.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026
Same journal

Automating laboratory developed tests using the panther fusion open access: Analytical and clinical evaluation of assays for the detection of viral causes of meningitis and encephalitis.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026
Same journal

Retrospective serology reveals chikungunya exposure among hospitalized dengue suspected cases in Minas Gerais, Brazil, 2024.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026
Same journal

Genomic epidemiology of two travel-associated pediatric measles viruses within the B3 Lineage.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026
See all related articles

Chronic fatigue syndrome (CFS) involves immune system abnormalities, HPA axis dysfunction, and potential links to infections and toxins. Early diagnosis and targeted treatments, like addressing viral infections, are crucial for managing this complex condition.

Area of Science:

  • Immunology
  • Neuroendocrinology
  • Infectious Disease

Background:

  • Chronic fatigue syndrome (CFS) affects 0.4-1% globally, with diagnosis relying on excluding other conditions.
  • Pathogenesis involves immune system abnormalities, HPA axis dysfunction, and potential triggers like infections and toxins.
  • Emotional stress plays a role in CFS development and HPA axis activation, but is distinct from depression.

Purpose of the Study:

  • To review the current understanding of Chronic Fatigue Syndrome (CFS) pathogenesis.
  • To highlight the importance of immune system abnormalities and emotional stress in CFS.
  • To outline priorities for future research and treatment development.

Main Methods:

  • Review of existing studies on CFS pathogenesis.

Related Experiment Videos

  • Analysis of factors contributing to CFS, including immune, neuroendocrine, and environmental aspects.
  • Examination of the role of emotional stress and its distinction from depression.

    • Main Results:

    • CFS pathogenesis involves immune activation, HPA axis dysfunction, and potential exogenous insults (infections, toxins).
    • Emotional stress is a significant factor influencing immune response and HPA axis activation in CFS.
    • Current treatments are limited, with specific treatment of virus infections being underutilized.

    Conclusions:

    • Understanding molecular pathogenesis through gene expression is a key research priority.
    • Development of protein biomarker-based diagnostic tests is needed.
    • Focus on developing specific curative treatments for CFS is essential.