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Updated: Jul 20, 2026

The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo
Published on: October 30, 2014
Role of centrifugal projections to the olfactory bulb in olfactory processing
Carly L Kiselycznyk1, Steven Zhang, Christiane Linster
1Department of Neurobiology and Behavior, Cornell University, Ithaca, New York, USA.
Abstract:
While there is evidence that feedback projections from cortical and neuromodulatory structures to the olfactory bulb are crucial for maintaining the oscillatory dynamics of olfactory bulb processing, it is not clear how changes in dynamics are related to odor perception. Using electrical lesions of the olfactory peduncle, sparing output from the olfactory bulb while decreasing feedback inputs to the olfactory bulb, we demonstrate here a role for feedback inputs to the olfactory bulb in the formation of odor-reward associations, but not for maintaining primary bulbar odor representations, as reflected by spontaneous odor discrimination.
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