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Updated: Jul 20, 2026

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior
Published on: April 16, 2014
Functional alignment of feedback effects from visual cortex to thalamus
Wei Wang1, Helen E Jones, Ian M Andolina
1Institute of Ophthalmology, University College London, Bath Street, London EC1V 9EL, UK.
Abstract:
Following from the classical work of Hubel and Wiesel, it has been recognized that the orientation and the on- and off-zones of receptive fields of layer 4 simple cells in the visual cortex are linked to the spatial alignment and properties of the cells in the visual thalamus that relay the retinal input. Here we present evidence showing that the orientation and the on- and off-zones of receptive fields of layer 6 simple cells in cat visual cortex that provide feedback to the thalamus are similarly linked to the alignment and properties of the receptive fields of the thalamic cells they contact. However, the pattern of influence linked to on- and off-zones is phase-reversed. This has important functional implications.
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