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Tomotherapeutic stereotactic body radiation therapy: Techniques and comparison between modalities
Martin Fuss1, Chengyu Shi, Niko Papanikolaou
1Department of Radiation Oncology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. fussm@ohsu.edu
Acta Oncologica (Stockholm, Sweden)
|September 20, 2006
Summary
Stereotactic body radiation therapy (SBRT) using helical and serial tomotherapy shows comparable plan quality and delivery times. Serial tomotherapy offers faster planning, while helical tomotherapy
Area of Science:
- Radiation Oncology
- Medical Physics
- Radiotherapy Technology
Background:
- Stereotactic body radiation therapy (SBRT) is an advanced radiation technique.
- Tomotherapy offers intensity-modulated radiation therapy (IMRT) capabilities.
- Both helical and serial tomotherapy modalities are used for SBRT planning and delivery.
Purpose of the Study:
- To compare helical and serial tomotherapy for SBRT.
- To evaluate dosimetric parameters, planning time, and delivery time.
- To assess the quality of megavoltage CT (MVCT) image-guidance.
Main Methods:
- Comparison of helical and serial tomotherapy plans for 12 SBRT patients.
- Dosimetric analysis of tumor and planning target volumes.
- Measurement of treatment planning and delivery times.
- Assessment of MVCT image-guidance for different target sites.
Main Results:
- Helical and serial tomotherapy plans demonstrated comparable plan quality.
- Serial tomotherapy planning was significantly faster (<1 hour) than helical tomotherapy (3.5 hours).
- Treatment delivery times were comparable, with minor differences (<10 min).
- MVCT image-guidance was effective for thoracic and spinal targets but limited for liver lesions due to poor soft-tissue contrast.
Conclusions:
- Both helical and serial tomotherapy are feasible for SBRT.
- Serial tomotherapy provides a more standardized and faster planning process.
- Plan quality and delivery efficiency are similar between the two tomotherapy modalities.
- MVCT image-guidance is valuable for bony and lung targets but less so for soft-tissue liver targets.
