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Clinical predictors for hearing loss in children with bacterial meningitis
J Walter Kutz1, Lawrence Mariano Simon, Sri Kiran Chennupati
1Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Tex, USA.
Insights
Sensorineural hearing loss affects 30.6% of children with bacterial meningitis, particularly those with Streptococcus pneumoniae. Early identification and rehabilitation are crucial for mitigating long-term challenges.
Area of Science:
- Pediatric Infectious Diseases
- Audiology
- Neurology
Background:
- Bacterial meningitis is a serious infection in children.
- Hearing loss is a known complication of bacterial meningitis.
- Risk factors and incidence require further elucidation.
Purpose of the Study:
- Identify clinical risk factors for hearing loss in pediatric bacterial meningitis.
- Determine the incidence of hearing loss in culture-proven bacterial meningitis.
- Compare clinical features between Streptococcus pneumoniae and Neisseria meningitidis meningitis.
Main Methods:
- Retrospective review of 171 children with bacterial meningitis over 10 years.
- Audiologic testing to assess sensorineural hearing loss.
- Analysis of clinical data and cerebrospinal fluid parameters.
Main Results:
- 30.6% of children experienced sensorineural hearing loss.
- Higher incidence in Streptococcus pneumoniae (35.9%) vs. Neisseria meningitidis (23.9%) meningitis.
- Hospitalization length, seizures, CSF protein/glucose predicted hearing loss.
Conclusions:
- Sensorineural hearing loss is a common sequela of pediatric bacterial meningitis.
- Early identification and rehabilitation are essential.
- Findings aid in managing long-term educational and social outcomes.
Objectives:
To identify clinical risk factors that predict a higher incidence of hearing loss in children with bacterial meningitis, to determine the overall incidence of hearing loss in a large group of children proven by culture findings to have bacterial meningitis, and to compare clinical characteristics among patients with Streptococcus pneumoniae meningitis and Neisseria meningitidis meningitis.
Design:
Retrospective review
Setting:
Tertiary pediatric hospital.
Patients:
A total of 171 children identified with bacterial meningitis who met inclusion criteria over a consecutive 10-year period.
Main Outcome Measure:
Presence of sensorineural hearing loss.
Results:
Of 134 patients who underwent audiologic testing during their initial hospitalization, 41 (30.6%) were found to have at least a unilateral mild sensorineural hearing loss. The incidence of hearing loss was greater in patients with S pneumoniae meningitis than in patients with N meningitidis meningitis (35.9% and 23.9%, respectively). Length of hospitalization, development of seizures, elevated cerebrospinal fluid protein, and decreased cerebrospinal fluid glucose were significant predictors for hearing loss in children with bacterial meningitis. These factors were not found to be as strong a predictor for hearing loss in patients with N meningitidis meningitis. Stability of hearing was demonstrated with limited follow-up audiometry.
Conclusions:
Sensorineural hearing loss is a common sequela in children with bacterial meningitis. Identification of hearing loss in children with bacterial meningitis and early rehabilitation will lessen the long-term educational and social difficulties these children may experience.
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