Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The exocytoskeleton.

Arthur L Koch1

  • 1Biology Department, Indiana University, Bloomington, IN 47405, USA. Koch@indiana.edu

Journal of Molecular Microbiology and Biotechnology
|September 20, 2006
PubMed
Summary
This summary is machine-generated.

The bacterial peptidoglycan (murein) sacculus is crucial for cell division and maintaining characteristic shapes. Its complex synthesis and localized growth are vital for bacterial survival and evolution.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stone age diseases and modern AIDS.

Virology journal·2008
Same author

Evolution of temperate pathogens: the bacteriophage/bacteria paradigm.

Virology journal·2007
Same author

Unidirectional movement of flares of cells of Myxococcus xanthus.

Critical reviews in microbiology·2006
Same author

Partition of old murein in small patches over the entire wall of E. coli cells forced to grow as a coccoid.

Current microbiology·2006
Same author

Future chemotherapy, with emphasis on bacterial murein.

FEMS immunology and medical microbiology·2006
Same author

The first cell.

Advances in microbial physiology·2005
Same journal

Immunogenicity Evaluation of Chimeric Subunit Vaccine Comprising Adhesion Coli Surface Antigens from Enterotoxigenic Escherichia coli.

Journal of molecular microbiology and biotechnology·2020
Same journal

Study of the Enzymatic Capacity of Kluyveromyces marxianus for the Synthesis of Esters.

Journal of molecular microbiology and biotechnology·2020
Same journal

Vaccination of Mice with Listeria ivanovii Expressing the Truncated M Protein of Porcine Reproductive and Respiratory Syndrome Virus Induces both Antigen-Specific CD4+ and CD8+ T Cell-Mediated Immunity.

Journal of molecular microbiology and biotechnology·2020
Same journal

Production of Mycobacterium bovis Antigens Included in Recombinant Occlusion Bodies of Baculovirus.

Journal of molecular microbiology and biotechnology·2020
Same journal

Enhanced Fermentable Sugar Production from Enteromorpha Polysaccharides by the Crude Enzymes of Vibrio sp. H11.

Journal of molecular microbiology and biotechnology·2020
Same journal

Characterization of Alanine Dehydrogenase and Its Effect on Streptomyces coelicolorA3(2) Development in Liquid Culture.

Journal of molecular microbiology and biotechnology·2019
See all related articles

Area of Science:

  • Microbiology
  • Cell Biology
  • Biochemistry

Background:

  • The murein (peptidoglycan) sacculus is essential for most bacterial life cycles.
  • Its importance arose with bacterial evolution from the Last Universal Ancestor, likely due to increasing cellular osmotic pressure.
  • The sacculus is synthesized outside the cytoplasmic membrane, requiring complex biochemical processes.

Purpose of the Study:

  • To highlight the essential role of the bacterial murein sacculus in cell growth and division.
  • To explain the evolutionary necessity of the peptidoglycan wall.
  • To describe the biochemical complexity and localized growth patterns of the murein sacculus.

Main Methods:

  • Review of existing literature on bacterial cell wall synthesis and evolution.

Related Experiment Videos

  • Analysis of the biochemical pathways involved in peptidoglycan construction.
  • Examination of the mechanisms controlling sacculus growth and cell division.

    • Main Results:

    • The murein sacculus is indispensable for bacterial survival, except in specific environmental conditions.
    • Peptidoglycan synthesis is a complex biochemical process vital for maintaining cell integrity.
    • Differential growth of the sacculus enables cell division and species-specific shape determination.

    Conclusions:

    • The bacterial murein sacculus is a key innovation essential for bacterial life, enabling division and characteristic morphology.
    • Understanding peptidoglycan synthesis is critical for comprehending bacterial physiology and evolution.
    • The localized growth of the sacculus is a fundamental aspect of bacterial cell biology.