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Updated: Jul 19, 2026
03:32
Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
Published on: December 27, 2024
Esophageal cancer after distal gastrectomy
N Hashimoto1, M Inayama, M Fujishima
1Department of Surgery, Kinki University, Osaka Sayama, Osaka, Japan. hashiline@aol.com
Summary
A history of gastrectomy, a surgery to remove part or all of the stomach, is linked to a higher incidence of lower esophageal squamous cell carcinoma. This suggests a potential association between prior stomach surgery and esophageal cancer development.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Duodenogastroesophageal reflux is a known complication after distal gastrectomy.
- The contribution of this reflux to esophageal cancer development in post-gastrectomy patients remains controversial.
Purpose of the Study:
- To investigate the effect of prior gastrectomy on the development of esophageal cancer.
- To determine if gastrectomy history is associated with specific tumor locations or types in the esophagus.
Main Methods:
- Retrospective evaluation of 153 patients who underwent subtotal esophagectomy for thoracic esophageal cancer.
- Patients were divided into two groups: those with a prior gastrectomy (n=14) and those without (n=139).
- Clinical data and histopathological examination of resected esophagi were analyzed.
Main Results:
- Patients with a history of gastrectomy showed a significantly higher proportion of lower-third esophageal tumors.
- The interval between gastrectomy and esophagectomy was shorter for gastric cancer (10.5 years) than for peptic ulcers (28.9 years).
- A trend towards shorter intervals was observed with Billroth I compared to Billroth II anastomosis, though not statistically significant.
Conclusions:
- A history of gastrectomy is associated with an increased risk of lower-third squamous cell esophageal carcinoma.
- These findings suggest a potential link between prior gastric surgery and the pathogenesis of specific esophageal cancers.
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