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Updated: Jul 19, 2026

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Principles of antimicrobial therapy.
1Department of Anatomy, Physiology, and Pharmacology, 109 Greene Hall, College of Veterinary Medicine, Auburn University, AL 36849, USA. boothdm@auburn.edu
Judicious antimicrobial use is crucial for successful treatment, which now includes preventing drug resistance alongside infection eradication. Achieving sufficient drug concentrations at the infection site ensures therapeutic success.
Area of Science:
- Microbiology
- Infectious Diseases
- Pharmacology
Background:
- Antimicrobial therapy aims to eradicate infections by achieving lethal drug concentrations.
- The definition of therapeutic success has evolved to encompass resistance prevention.
Purpose of the Study:
- To highlight the importance of judicious antimicrobial use.
- To redefine therapeutic success in antimicrobial therapy.
Main Methods:
- Literature review on antimicrobial use and resistance.
- Analysis of the definition of therapeutic success.
Main Results:
- Judicious antimicrobial use is essential for successful treatment outcomes.
- Therapeutic success now requires both infection eradication and resistance avoidance.
Conclusions:
- Antimicrobial stewardship is key to preserving treatment efficacy.
- A comprehensive definition of success ensures long-term effectiveness of antimicrobial drugs.
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