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Updated: Jul 19, 2026

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Use of Electromagnetic Navigational Transthoracic Needle Aspiration (E-TTNA) for Sampling of Lung Nodules
Published on: May 23, 2015
CT-guided transthoracic needle biopsy using a puncture site-down positioning technique
Fumiko Kinoshita1, Takashi Kato, Kimihiko Sugiura
1Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago, Tottori 683-8506, Japan. fkino@luke.or.jp
AJR. American Journal of Roentgenology
|September 21, 2006
Summary
A new puncture site-down positioning technique for CT-guided transthoracic needle biopsy significantly reduces pneumothorax complications. This method maintains high diagnostic accuracy, offering a safer alternative for lung lesion biopsies.
Area of Science:
- Radiology
- Pulmonary Medicine
- Interventional Oncology
Background:
- CT-guided transthoracic needle biopsy (CT-TTNB) is crucial for diagnosing lung lesions.
- The standard technique carries risks, including pneumothorax.
- Minimizing complications while maintaining diagnostic yield is a key objective.
Purpose of the Study:
- To evaluate the efficacy and safety of a novel puncture site-down positioning technique for CT-TTNB.
- To compare this new technique against the standard CT-TTNB approach.
Main Methods:
- Retrospective analysis of 236 CT-guided transthoracic needle biopsies.
- Comparison between standard technique (89 cases) and puncture site-down positioning technique (147 cases).
- Utilized a 20-gauge automated cutting needle without coaxial technique for all biopsies.
Main Results:
- Both techniques demonstrated high diagnostic accuracy (94.4% standard vs. 94.6% new).
- The puncture site-down technique significantly reduced pneumothorax rates (12.9% vs. 41.6%) and chest tube placement (2.7% vs. 18.0%).
- Sensitivity for malignant and benign lesions remained comparable between the two methods.
Conclusions:
- CT-guided transthoracic needle biopsy with puncture site-down positioning is safe and effective.
- This technique offers high diagnostic accuracy with a notably lower complication rate, particularly for pneumothorax.
- The puncture site-down method represents an improvement for CT-guided lung biopsies.
