Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
Menopause01:28

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the Use of Remodelable Pericardial Bolsters during Cystectomy and Diversion to Prevent Enterocutaneous Fistulas.

Urology practice·2023
Same author

Editor's Note: p38 Mitogen-Activated Protein Kinase-Driven MAPKAPK2 Regulates Invasion of Bladder Cancer by Modulation of MMP-2 and MMP-9 Activity.

Cancer research·2022
Same author

Retraction notice to "Differential effects of valproic acid on growth, proliferation and metastasis in HTB-5 and HTB-9 bladder cancer cell lines" [Canc. Lett. 281/2 (2009) 196-202].

Cancer letters·2021
Same author

A Retrospective Study of Patients Undergoing Radical Cystectomy and Receiving Peri-Operative Naloxegol or Alvimopan: Comparison of Length of Stay.

Journal of surgery (New York, N.Y.)·2018
Same author

Altered expression and modulation of the two-pore-domain (K<sub>2P</sub>) mechanogated potassium channel TREK-1 in overactive human detrusor.

American journal of physiology. Renal physiology·2017
Same author

The Prognostic Value of Previous Irradiation on Survival of Bladder Cancer Patients.

Bladder cancer (Amsterdam, Netherlands)·2016

Related Experiment Video

Updated: Jul 19, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Downsizing and prostate cancer.

Shandra Wilson

    Reviews in Urology
    |September 21, 2006
    PubMed
    Summary

    Neoadjuvant androgen deprivation therapy offers clinical benefits for prostate cancer. Gonadotropin-releasing hormone antagonists provide faster testosterone suppression than agonists, improving treatment outcomes.

    Area of Science:

    • Oncology
    • Urology

    Background:

    • Neoadjuvant androgen deprivation therapy (ADT) is used for prostatic carcinoma.
    • It offers clinical and quality-of-life benefits.

    Purpose of the Study:

    • Compare gonadotropin-releasing hormone (GnRH) antagonists with GnRH agonists in neoadjuvant ADT.
    • Highlight the advantages of GnRH antagonists.

    Main Methods:

    • Review of clinical data comparing GnRH antagonists and agonists.
    • Analysis of efficacy in apoptosis, radiation sensitization, and prostate volume reduction.

    Main Results:

    • GnRH antagonists achieve castrate testosterone levels faster than GnRH agonists.
    • GnRH antagonists avoid the risk of testosterone flare.

    More Related Videos

    Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
    13:19

    Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

    Published on: November 2, 2013

    Murine Prostate Micro-dissection and Surgical Castration
    08:49

    Murine Prostate Micro-dissection and Surgical Castration

    Published on: May 11, 2016

    Related Experiment Videos

    Last Updated: Jul 19, 2026

    A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
    07:25

    A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

    Published on: March 6, 2018

    Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
    13:19

    Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

    Published on: November 2, 2013

    Murine Prostate Micro-dissection and Surgical Castration
    08:49

    Murine Prostate Micro-dissection and Surgical Castration

    Published on: May 11, 2016

  • Efficacy in apoptosis, radiation sensitization, and prostate volume reduction is equal or superior with GnRH antagonists.

    • Conclusions:

    • GnRH antagonists are increasingly used by urologists for neoadjuvant ADT.
    • They are employed in patients undergoing prostatectomy, radiation, brachytherapy, and cryotherapy.
    • This therapy improves outcomes in prostate cancer treatment.