Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Best practice & research. Clinical gastroenterology. Advances in diagnostic assessment of the oesophageal mucosa. Preface.

Best practice & research. Clinical gastroenterology·2008
Same author

Does Helicobacter pylori infection influence response rate or speed of symptom control in patients with gastroesophageal reflux disease treated with rabeprazole?

Scandinavian journal of gastroenterology·2006
Same author

Evidence for pooling of gastric secretions in the proximal stomach in humans using single photon computed tomography.

Gastroenterology·2002
Same author

Comparative optical coherence tomography imaging of human esophagus: how accurate is localization of the muscularis mucosae?

Gastrointestinal endoscopy·2002
Same author

The stool antigen test for detection of Helicobacter pylori after eradication therapy.

Annals of internal medicine·2002
Same author

Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease.

Gastroenterology·2002

Related Experiment Video

Updated: Jul 19, 2026

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
03:32

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Published on: December 27, 2024

Long-term GERD management: the individualized approach.

Guido Tytgat1

  • 1Academic Medical Center, Amsterdam, The Netherlands.

Drugs of Today (Barcelona, Spain : 1998)
|September 21, 2006
PubMed
Summary

Proton pump inhibitors (PPIs) effectively manage gastroesophageal reflux disease (GERD). Tailored treatment, including standard or half-dose PPIs and on-demand therapy, ensures symptom resolution and remission for both erosive and nonerosive reflux disease.

Related Experiment Videos

Last Updated: Jul 19, 2026

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
03:32

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Published on: December 27, 2024

Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • Gastroesophageal reflux disease (GERD) requires individualized treatment strategies.
  • Assessing disease severity and treatment impact involves evaluating mucosal lesions and symptoms.

Purpose of the Study:

  • To outline an individualized treatment approach for GERD using proton pump inhibitors (PPIs).
  • To define treatment duration and maintenance strategies for both erosive and nonerosive reflux disease (NERD).

Main Methods:

  • Standard-dose PPI therapy until symptom resolution (NERD) or complete remission (erosive GERD).
  • Half-dose PPI maintenance therapy for both erosive esophagitis and NERD.
  • On-demand PPI therapy for NERD patients in remission.
  • Return to full-dose PPI for symptom relapse.

Main Results:

  • Standard-dose PPIs are effective for initial GERD management.
  • Half-dose PPIs maintain remission in both erosive and nonerosive GERD.
  • On-demand PPI therapy is a viable option for stable NERD patients.
  • Long-term PPI use is safe and effective for maintaining GERD remission.

Conclusions:

  • Individualized, tailored treatment with PPIs is crucial for effective GERD management.
  • Both standard and maintenance (half-dose) PPI regimens are effective.
  • Long-term PPI therapy demonstrates safety and efficacy in maintaining GERD remission.