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Related Concept Videos

Mechanisms of Retrovirus-induced Cancers01:51

Mechanisms of Retrovirus-induced Cancers

Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
Mechanisms of Retrovirus-induced Cancers01:51

Mechanisms of Retrovirus-induced Cancers

Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Introduction to Virus01:28

Introduction to Virus

Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

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Updated: Jul 19, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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Published on: January 7, 2019

Understanding how viruses can cause malignant disease.

Kenneth Campbell1

  • 1Leukaemia Research Fund.

Nursing Times
|September 22, 2006
PubMed
Summary

Viral infections significantly contribute to the global cancer burden, particularly in developing nations. Increased support for vaccination programs, especially through the World Health Organization, can reduce cancer incidence worldwide.

Area of Science:

  • Oncology
  • Infectious Diseases
  • Public Health

Background:

  • Viral infections are a significant, yet often overlooked, contributor to the global cancer burden.
  • The impact of virally-induced cancers disproportionately affects developing countries with limited resources for prevention.

Purpose of the Study:

  • To highlight the substantial role of viral infections in the global cancer burden.
  • To emphasize the need for enhanced vaccination programs in developing nations to mitigate cancer incidence.

Main Methods:

  • This article is a discussion-based review.
  • It synthesizes existing data on viral oncogenesis and cancer epidemiology.
  • It analyzes the economic and public health implications of viral-induced cancers.

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Merkel Cell Polyomavirus Infection and Detection

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Last Updated: Jul 19, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
12:42

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Published on: January 7, 2019

Handling of the Cotton Rat in Studies for the Pre-clinical Evaluation of Oncolytic Viruses
06:13

Handling of the Cotton Rat in Studies for the Pre-clinical Evaluation of Oncolytic Viruses

Published on: November 24, 2014

Merkel Cell Polyomavirus Infection and Detection
13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

Main Results:

  • Viral infections are a major driver of cancer globally.
  • Developing countries bear the highest burden of virally-induced cancers due to challenges in funding vaccination programs.
  • International support for vaccination initiatives can significantly decrease cancer rates.

Conclusions:

  • Addressing the global cancer burden requires a concerted effort to combat viral infections through widespread vaccination.
  • Financial and logistical support from wealthier nations for vaccination programs is crucial for reducing cancer incidence, especially in resource-limited settings.
  • Collaboration through organizations like the World Health Organization can maximize the impact of global health initiatives on cancer prevention.