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Coupling daunorubicin to monoclonal antialphafoetoprotein with a new activated derivative
1Department of Biochemistry, Faculty of Medicine, Université Laval, Sainte-Foy, Québec, Canada.
International Journal of Immunopharmacology
|January 1, 1990
Abstract:
We report the synthesis of daunorubicin antialphafoetoprotein conjugates, using a new coupling method. At equimolar concentrations on AFP producing cells in vitro, these conjugates were found three times as cytotoxic as the free drug.
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