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Updated: Jul 19, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Photoparoxysmal responses in children with chromosomal aberrations
Salvatore Grosso1, Lucia Pucci, Gabriella Bartalini
1Department of Pediatrics, Obstetrics, and Reproductive Medicine, University of Siena, Viale M. Bracci, 53100 Siena, Italy. grosso@unisi.it
Abstract:
Electroencephalographic (EEG) anomalies and epilepsy are commonly observed in the clinical picture of patients with chromosomal aberrations. However, no investigations have been performed on the relationship between chromosomal disorders and photoparoxysmal response (PPR). In this study, we evaluate the characteristics of PPRs elicited with intermittent photic stimulation during a routine electroencephalogram in children affected by chromosomal anomalies and correlated this with the clinical profile of the child. A review of the literature has also been performed. PPRs occurred in 14% (4/28) of patients. PPRs were brief (
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