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Updated: Jul 19, 2026

Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Lacrimal sac metastases from renal cell carcinoma
M T Vozmediano-Serrano1, N Toledano-Fernández, M J Fdez-Aceñero
1Department of Ophthalmology, Hospital General of Móstoles, Madrid, Spain.
Purpose:
To report the first case of metastasis from renal cell carcinoma to the lacrimal sac and review the therapeutic options.
Methods:
We have reviewed the case of a woman who was operated on for a renal cell carcinoma that developed epiphora and a lacrimal sac tumor, which corresponded to a metastasis from her previous tumor. Although renal cell carcinoma shows a great tendency for distant metastasis, this is the first reported case of metastasis to the lacrimal sac.
Results:
We comment on the rarity of the case and on the therapeutic alternatives for these cases according to the reviewed literature.
Conclusion:
Metastasis to the lacrimal sac are rather infrequent and should be borne in mind on the appearance of a tumor in this location in people with a history of malignancy.

