Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visual function in human ocular toxoplasmosis.

Janine Scherrer1, Milko E Iliev, Markus Halberstadt

  • 1Department of Ophthalmology, University of Bern, Bern, Switzerland.

The British Journal of Ophthalmology
|September 22, 2006
PubMed
Summary

Inactive ocular toxoplasmosis causes permanent visual field defects in most patients. Standard automated perimetry is more sensitive than visual acuity in detecting this damage.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of key baseline disease characteristics on aflibercept 8 mg dosing interval extension: A post hoc 96-week analysis of PULSAR.

Ophthalmology. Retina·2026
Same author

Discontinuing Anti-VEGF Therapy in Patients with Neovascular Age-Related Macular Degeneration That Remains Inactive with Treatment at the Maximum Injection Interval.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Ocular sarcoidosis: from clinical signs to targeted interventions.

Current opinion in immunology·2026
Same author

Six-Month Real-World Data in Macular Edema Due to Retinal Vein Occlusion Treated with Faricimab: Swiss Retina Research Network Report.

Ophthalmology and therapy·2026
Same author

Vascular remodeling of macular neovascularization following switch to intravitreal faricimab in neovascular AMD.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Clusters of postoperative endophthalmitis caused by non-tuberculous mycobacteria and Pseudomonas aeruginosa: diagnostic and sterilization challenges.

Journal of ophthalmic inflammation and infection·2026

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Ocular toxoplasmosis is an infection that can cause inflammation and damage to the eye.
  • While often treated, the long-term effects on vision, especially in the inactive stage, require further assessment.

Purpose of the Study:

  • To evaluate the extent of visual impairment, specifically visual acuity reduction and visual field defects, in patients with inactive ocular toxoplasmosis.
  • To compare the sensitivity of visual acuity testing versus standard automated perimetry in detecting functional damage.

Main Methods:

  • A prospective, cross-sectional study included 61 patients with quiescent ocular toxoplasmosis.
  • Comprehensive ophthalmic examinations, retinal photodocumentation, and standard automated perimetry were conducted.

Related Experiment Videos

  • Visual acuity and visual field damage were classified using standardized criteria.

    • Main Results:

    • Out of 69 evaluated eyes, 94% showed visual field damage, while only 41% had reduced visual acuity.
    • Standard automated perimetry was significantly more sensitive (p<0.001) than visual acuity in detecting chorioretinal damage.
    • Moderate to severe functional impairment affected 65.2% of eyes based on visual fields, compared to 27.5% based on visual acuity.

    Conclusions:

    • Inactive ocular toxoplasmosis is frequently associated with persistent visual field deficits.
    • Standard automated perimetry appears to be a more effective tool than visual acuity for assessing functional impairment in ocular toxoplasmosis.