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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Mild cognitive impairment: what's in a name?
E Dierckx1, S Engelborghs, R De Raedt
1Developmental and Lifespan Psychology, Vrije Universiteit Brussel, Brussels, Belgium. eva.dierckx@vub.ac.be
Background:
Nowadays the term mild cognitive impairment (MCI) is used to fill the gap between cognitive changes associated with normal ageing and those associated with dementia. Despite some agreement in general definitions, MCI is still a heterogeneous clinical syndrome for which no DSM-IV criteria have yet been established. Criteria by Petersen et al. are presently the most applied in clinical practice. Moreover, little attention has been paid to the specific relation between MCI and depression.
Objective:
This review highlights some concerns about the concept of MCI and provides guidelines within the field of neuropsychology to solve them. In a second part, the paper focuses on the specific relationship between depression in the elderly and MCI.
Results:
We hypothesize that certain test instruments can be used to operationalize the criteria proposed by Petersen et al. Moreover, we suggest that cued recall might be of help to differentiate between progressive and non-progressive MCI. Concerning the specific relation between depression and MCI, we assume that elderly depression with concomitant cognitive problems can be seen as an MCI.
Conclusion:
The proposed adjustments and additions (neuropsychological instruments and the incorporation of depressive symptoms) in the diagnostic flowchart of Petersen may serve as useful tools for clinicians when making a diagnosis of MCI.
Insights
Mild cognitive impairment (MCI) is a heterogeneous syndrome. This review suggests incorporating neuropsychological tests and depressive symptoms into diagnostic criteria to improve MCI identification in the elderly.
Area of Science:
- Neuropsychology
- Geriatric Medicine
- Cognitive Science
Background:
- Mild cognitive impairment (MCI) bridges normal aging and dementia but lacks standardized criteria.
- Current diagnostic approaches, like Petersen's criteria, are widely used but require refinement.
- The interplay between MCI and depression in older adults remains under-explored.
Purpose of the Study:
- To address concerns regarding the conceptualization of MCI.
- To propose guidelines for neuropsychological assessment of MCI.
- To examine the relationship between elderly depression and MCI.
Main Methods:
- Review of existing literature and diagnostic criteria for MCI.
- Hypothesizing the utility of specific neuropsychological instruments.
- Suggesting modifications to diagnostic flowcharts.
Main Results:
- Certain neuropsychological tests can operationalize Petersen's MCI criteria.
- Cued recall memory tests may distinguish progressive from non-progressive MCI.
- Elderly depression with cognitive deficits aligns with MCI characteristics.
Conclusions:
- Integrating specific neuropsychological instruments enhances MCI diagnosis.
- Including depressive symptoms in diagnostic criteria improves MCI identification.
- Proposed adjustments offer practical tools for clinicians diagnosing MCI.
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