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Published on: December 11, 2017
Infective endocarditis of native valve after anterior nasal packing
Suriya Jayawardena1, Jacob Eisdorfer, Shalaka Indulkar
1Department of Medicine, Coney Island Hospital, Maimonides Medical Center, Brooklyn, NY 11235, USA. suriyakbrsj@yahoo.com
Abstract:
We present a case report of a patient who was previously treated for spontaneous epistaxis with a petroleum jelly gauze (0.5 in x 72 in) anterior nasal packing filled with an antibiotic ointment, along with prophylactic oral clindamycin. The patient presented with fever and hypotension 3 days after the nasal packing. Her blood cultures grew methicillin-resistant Staphylococcus aureus and the transesophageal echocardiography showed vegetation on the atrial surface of the posterior mitral valve leaflet, confirming the diagnosis of bacterial endocarditis attributable to nasal packing. Several case reports discuss toxic shock syndrome after nasal packing, but none describe endocarditis of the native heart valves subsequent to anterior nasal packing. Current guidelines on endocarditis prophylaxis produced by the American Heart Association, European Cardiac Society, and British Cardiac Society together with published evidence do not recommend endocarditis prophylaxis for patients with native heart valves undergoing anterior nasal packing.
Insights
This case report highlights a rare instance of bacterial endocarditis following anterior nasal packing. Methicillin-resistant Staphylococcus aureus (MRSA) infection developed despite prophylactic antibiotics, underscoring potential risks.
Area of Science:
- Infectious Diseases
- Cardiology
- Otolaryngology
Background:
- Anterior nasal packing is a common treatment for epistaxis.
- Current guidelines do not recommend endocarditis prophylaxis for native heart valves during anterior nasal packing.
- Toxic shock syndrome is a known complication of nasal packing.
Observation:
- A patient developed fever and hypotension three days after anterior nasal packing with antibiotic-infused gauze.
- Blood cultures revealed methicillin-resistant Staphylococcus aureus (MRSA).
- Transesophageal echocardiography identified vegetation on the mitral valve, confirming bacterial endocarditis.
Findings:
- This case represents the first reported instance of native valve bacterial endocarditis secondary to anterior nasal packing.
- The infection was attributed to MRSA originating from the nasal packing.
- Prophylactic oral clindamycin did not prevent the development of endocarditis.
Implications:
- This case suggests a potential, albeit rare, risk of bacterial endocarditis following anterior nasal packing, even with prophylactic measures.
- It may prompt a re-evaluation of prophylaxis strategies for specific patient populations.
- Further research is needed to understand the mechanisms and incidence of this complication.
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