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Related Experiment Videos

Factor V inhibitor: case report.

Barbara Leus1, Katrien Devreese, Jan van den Bossche

  • 1Clinical Laboratory, General Hospital Middelheim, Antwerp, Belgium. barbaraleus@hotmail.com

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|September 22, 2006
PubMed
Summary
This summary is machine-generated.

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Acquired inhibitors targeting factor V are rare, with most cases linked to bovine thrombin. This report details a patient who developed a factor V inhibitor post-surgery, highlighting unpredictable disease progression.

Area of Science:

  • Hematology
  • Immunology

Background:

  • Acquired inhibitors to coagulation factors are uncommon, particularly those targeting factor V.
  • Approximately 150 cases of factor V inhibitors have been documented, predominantly associated with bovine thrombin exposure.

Observation:

  • A case report of a patient developing a factor V inhibitor during the postoperative period is presented.
  • The patient's clinical condition and disease progression were unpredictable.

Findings:

  • The study reviews potential etiologies, diverse clinical presentations, and therapeutic options for factor V inhibitors based on existing literature.
  • This case illustrates the often unpredictable nature of disease progression in individuals with factor V inhibitors.

Implications:

Related Experiment Videos

  • Understanding the rare occurrence and unpredictable nature of factor V inhibitors is crucial for clinical management.
  • This case underscores the importance of considering acquired factor V inhibitors in postoperative patients with unexplained bleeding or coagulation abnormalities.