Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 19, 2026

Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
12:22

Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

Cross-linked hydrogels for middle ear packing.

Albert H Park1, Adrienne Jackson, Lisa Hunter

  • 1Division of Otolaryngology-Head and Neck Surgery, University of Utah, School of Medicine, Salt Lake City, Utah 84132, USA. pcapark@ihc.com

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [And] European Academy of Otology and Neurotology
|September 22, 2006
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dried Blood Spot Testing in Confirmed Congenital Cytomegalovirus Discovered by Expanded Targeted Testing.

JAMA otolaryngology-- head & neck surgery·2026
Same author

Structural and functional connectivity in infancy relate to communication skills at age 2 in children born very preterm.

medRxiv : the preprint server for health sciences·2026
Same author

Reverse Transcriptase Activity with CRISPR (REACTR) Assay for Rapid and User-Friendly Therapeutic Drug Monitoring in Cytomegalovirus Care.

ACS infectious diseases·2026
Same author

Pharmacokinetics and Pharmacodynamics of (Val)Ganciclovir in Infants with Congenital Cytomegalovirus.

medRxiv : the preprint server for health sciences·2026
Same author

Precision Balance Rehabilitation in Progressive Multifocal Leukoencephalopathy: A Novel Case Report.

International medical case reports journal·2026
Same author

Molecular markers of pediatric cholesteatoma: A gene expression comparison with adult tissue.

International journal of pediatric otorhinolaryngology·2026

Carbylan-SX (P-C) shows promise as a supportive packing material for otologic surgery. It offers easier placement and less fibrosis compared to Gelfoam (P-GF) and Merogel (P-MG) in a guinea pig model.

Area of Science:

  • Otolaryngology
  • Biomaterials Science
  • Surgical Innovation

Background:

  • Effective supportive packing is crucial for successful otologic procedures like ossiculoplasty and tympanoplasty.
  • Current materials may present challenges in handling and biocompatibility.

Purpose of the Study:

  • To evaluate Carbylan-SX (P-C) as a potential supportive packing material for otologic surgery.
  • To compare P-C with Gelfoam (P-GF) and Merogel (P-MG) in a guinea pig model.

Main Methods:

  • Three materials (P-C, P-GF, P-MG) were implanted in guinea pig middle ears.
  • Auditory brainstem response and histological analyses were performed post-implantation.

Main Results:

  • Carbylan-SX (P-C) and Gelfoam (P-GF) were easily placed; Merogel (P-MG) was difficult to handle.

More Related Videos

Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture
10:54

Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture

Published on: January 17, 2017

Related Experiment Videos

Last Updated: Jul 19, 2026

Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
12:22

Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture
10:54

Tunable Hydrogels from Pulmonary Extracellular Matrix for 3D Cell Culture

Published on: January 17, 2017

  • P-C and P-MG showed the lowest levels of fibrosis.
  • Osteogenesis was similar across all tested materials.

    • Conclusions:

    • Carbylan-SX (P-C) demonstrates potential as an ideal supportive packing material for otologic procedures.
    • P-C offers advantages in ease of placement and reduced fibrosis compared to P-GF and P-MG.