[Efficacy of SMC-electrophoresis of peat mud in primary chronic duodenitis]

Area of Science:

• Gastroenterology
• Biophysics

Background:

• Primary chronic duodenitis affects the duodenal lining, causing inflammation and discomfort.
• Current treatment options may have limitations, necessitating exploration of novel therapeutic modalities.

Purpose of the Study:

• To evaluate the efficacy of sinusoidal modulated current (SMC) electrophoresis of peat mud as a monotherapy for primary chronic duodenitis.
• To investigate the impact of this therapy on duodenal mucosa, gastric function, and hormonal balance.

Main Methods:

• Sixty-five patients with primary chronic duodenitis received SMC electrophoresis using peat mud diluted with distilled water.
• Evaluations included fibrogastroduodenoscopy, duodenal biopsy analysis (morphology, element composition), gastric acid production assessment, and hormonal profile and collagen metabolism studies.

Main Results:

• Positive clinical and endoscopic changes were observed in patients treated with SMC electrophoresis.
• Histological examination revealed improvements in duodenal mucosa morphology.
• The therapy led to favorable shifts in hormonal status and normalization of collagen metabolism.

Conclusions:

• SMC electrophoresis of peat mud demonstrates therapeutic potential as a monotherapy for primary chronic duodenitis.
• Observed benefits are attributed to improved hormonal status and normalized collagen metabolism in the duodenal mucosa.