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Is global measles eradication feasible?
1Sabin Vaccine Institute and Pan American Health Organization, Washington, DC, USA. ciro.dequadros@sabin.org
Abstract:
Measles is one of most infectious diseases. Before the introduction of the measles vaccine, practically all children in the long run contracted measles. By the end of the 1980s most countries of the world had incorporated measles vaccine into their routine vaccination programs. Globally, some 800,000 deaths due to measles still occur every year, half of them in Africa. Eradication of measles would play an important role in improving child survival. The goal to eradicate measles from the Americas was set by the Pan American Sanitary Conference in 1994. Progress to date has been remarkable. Measles is no longer an endemic disease in the Americas and interruption of transmission has been documented in most countries. As of August 2005, 3 years have elapsed since the detection of the last indigenous case in Venezuela in September 2002. This experience shows that interruption of measles transmission can be achieved and sustained over a long period of time and that global eradication is feasible if appropriate strategy is implemented. Even in a new paradigm in which eradication is not followed by the discontinuation of vaccination, eradication of measles will be a good investment to avoid expensive epidemics and save the almost one million children that die every year to infection with the measles virus. It is not a dream to think that we will se a world free of measles by the year 2015.
Insights
Measles vaccination has dramatically reduced disease incidence. Global measles eradication is feasible, preventing hundreds of thousands of child deaths annually and costly epidemics.
Area of Science:
- Public Health
- Infectious Diseases
- Vaccinology
Background:
- Measles is a highly contagious disease, historically infecting nearly all children.
- Despite widespread vaccination programs since the 1980s, 800,000 deaths annually, primarily in Africa, highlight the need for eradication.
- Child survival rates can be significantly improved by eliminating measles.
Purpose of the Study:
- To assess the feasibility and impact of measles eradication.
- To review progress towards measles elimination in the Americas.
Main Methods:
- Analysis of global vaccination program data.
- Review of measles transmission interruption in the Americas since 1994.
- Case study of Venezuela's last indigenous measles case in 2002.
Main Results:
- Measles is no longer endemic in the Americas, with transmission interrupted in most countries.
- Three years have passed since the last indigenous measles case in Venezuela (September 2002).
- Sustained interruption of measles transmission is achievable.
Conclusions:
- Global measles eradication is feasible with appropriate strategies.
- Eradication is a worthwhile investment to prevent child mortality and costly epidemics.
- A measles-free world is an attainable goal.
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