Related Experiment Video
Updated: Jul 19, 2026

03:47
A Translational Surgical Porcine Model for Postoperative Intra-Abdominal Adhesion Formation
Published on: March 13, 2026
Adhesive intestinal obstruction
1Moi University Medical School, P.O. Box, 4606-30100, Eldoret, Kenya.
East African Medical Journal
|September 23, 2006
Summary
Adhesive intestinal obstruction is a significant surgical issue, often stemming from prior abdominal surgeries. Inadequate fluid therapy and delayed surgical intervention present major management challenges.
Area of Science:
- General Surgery
- Gastroenterology
- Surgical Pathology
Background:
- Adhesions following abdominal and pelvic surgery are a primary cause of intestinal obstruction.
- The incidence of adhesion-related intestinal obstruction is increasing in clinical practice.
Purpose of the Study:
- To assess the prevalence of adhesive intestinal obstruction.
- To identify previous surgical procedures in affected patients.
- To evaluate treatment outcomes and management factors for adhesion-related intestinal obstruction.
Main Methods:
- Retrospective descriptive study design.
- Data collected from Moi Teaching and Referral Hospital (MTRH), Kenya.
- Analysis of 93 patients managed for adhesive intestinal obstruction.
Main Results:
- Abdominal distension, bilious vomiting, absolute constipation, and pain were key symptoms.
- 45% of patients underwent surgery, with 59% delayed over 72 hours.
- 8% experienced ischemic gut injury; 92% received inadequate fluid therapy.
Conclusions:
- Adhesion-related intestinal obstruction is a common surgical problem at MTRH, Eldoret.
- Inadequate fluid management and delayed surgical intervention are critical challenges.
- This highlights the need for improved patient management protocols.
Related Concept Videos
Intestinal Obstruction I: Introduction
Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology
Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Inflammatory Bowel Disease V: Surgical Management
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
Appendicitis-I: Introduction
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Pyloric Obstruction
Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...

